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NHS PEG alkyne, Mp 3000 - 100mg

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NHS-PEG-Alkyne (Mw 3000) is a heterobifunctional polyethylene glycol (PEG) linker containing a succinimidyl ester (NHS) on one end and an alkyne group on the other. This reagent enables efficient bioconjugation between amine-containing molecules (such as proteins or peptides) and azide-functionalized compounds via click chemistry (CuAAC). The PEG spacer (molecular weight ~3000 Da) enhances water solubility, reduces steric hindrance, and improves biocompatibility in crosslinking and labeling reactions.

Key Features:

  • Product Name: NHS-PEG-Alkyne
  • Molecular Weight (Mw): 3000
  • Quantity: 100 mg
  • Functional Groups: NHS ester and terminal alkyne
  • High purity for reliable and reproducible conjugation
  • Soluble in water, DMSO, and DMF
  • Storage: –20°C, protected from moisture
  • For Research Use Only (RUO)

Applications:

  • PEGylation of biomolecules and surfaces
  • Amine-to-azide bioconjugation via click chemistry
  • Nanoparticle and hydrogel surface modification
  • Antibody or peptide functionalization
  • Controlled drug carrier or biosensor development (non-therapeutic)

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Internal Reference: 26127-100